@article{203356, author = {N JayaNandanan and Elizabeth Gavis and Veit Riechmann and Maria Leptin}, title = {A genetic in vivo system to detect asymmetrically distributed RNA.}, abstract = {
Many RNAs show polarized or otherwise non-random subcellular distributions. To create a method for genome-wide genetic screens for RNAs with asymmetric subcellular distributions, we have combined methods for gene tagging and live imaging of messenger RNA (mRNA). A pilot screen in a highly polarized, differentiated cell in the Drosophila larva, the branched terminal cell of the tracheal system, demonstrates the feasibility of the method for identifying new asymmetrically localized mRNAs in vivo.
}, year = {2011}, journal = {EMBO reports}, volume = {12}, pages = {1167-74}, month = {10/2011}, issn = {1469-3178}, doi = {10.1038/embor.2011.178}, language = {eng}, }